Researchers uncover early results about an existing tuberculosis vaccine that has been hypothesized to help against the coronavirus

While scientists race to develop and test a vaccine effective against SARS-CoV-2, the virus that causes COVID-19, recent studies have indicated that countries with widespread BCG vaccination appear to be weathering the pandemic better than their counterparts. This has led many researchers to suspect that BCG vaccine, which immunizes against tuberculosis, might offer protection against […]

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Designed antiviral proteins inhibit SARS-CoV-2 in the lab

Computer-designed small proteins have now been shown to protect lab-grown human cells from SARS-CoV-2, the coronavirus that causes COVID-19. In the experiments, the lead antiviral candidate, named LCB1, rivaled the best-known SARS-CoV-2 neutralizing antibodies in its protective actions. LCB1 is currently being evaluated in rodents. Coronaviruses are studded with so-called Spike proteins. These latch onto […]

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Genome analyses track SARS-CoV-2’s early introduction to the US and Europe

SARS-CoV-2 arrived in Washington State somewhere between late January and early February 2020, sparking rapid community transmission of the virus that went undetected for several weeks before this community spread became evident, prompting a change in testing criteria to emphasize individuals with no travel history. That’s the scenario proposed by Trevor Bedford and colleagues after […]

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COVID-19 study links strict social distancing to much lower chance of infection

Using public transportation, visiting a place of worship, or otherwise traveling from the home is associated with a significantly higher likelihood of testing positive with the coronavirus SARS-CoV-2, while practicing strict social distancing is associated with a markedly lower likelihood, suggests a study from researchers at the Johns Hopkins Bloomberg School of Public Health. For […]

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Small study shows convalescent plasma is safe to use in pediatric patients with COVID-19

Early findings from researchers at Children’s Hospital of Philadelphia (CHOP) show that convalescent plasma appears to be a safe and possibly effective treatment for children with life-threatening cases of COVID-19. The results were published online Friday by the journal Pediatric Blood and Cancer. To date, no therapies have been proven safe and effective for children […]

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Preliminary results from Russian trials find that vaccine candidates led to no serious adverse events and elicit antibody response

Results from two early-phase Russian non-randomised vaccine trials (Sputnik V) in a total of 76 people are published today in The Lancet, finding that two formulations of a two-part vaccine have a good safety profile with no serious adverse events detected over 42 days, and induce antibody responses in all participants within 21 days. Secondary […]

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